Endocrine Abstracts

Background: The association between Graves’ disease and thymic hyperplasia is well documented in the literature. Despite that it remains largely unrecognized in routine clinical practice. The lack of familiarity of usually benign nature of thymic hyperplasia associated with Graves’ disease may result in an aggressive management course, along with associated risks.Case presentation: A previously healthy 32-year-old female was admitted to hospita...

Introduction: Brown tumour is a rare, benign, tumour-like lesion of bones.The presence of brown tumour is a rare complication of uncontrolled primary, secondary or tertiary hyperparathyroidism.Brown tumours can be solitary or multifocal and are most commonly located in ribs, clavicles, pelvic girdle, extremities and facial bones (maxilla, mandible, and hard palate).A diagnosis of brown tumour in hyperparathyroidism is established by evaluation of serum calcium, phosphorus and ...

Primary hyperparathyroidism (PHPT) is nowadays usually diagnosed as an asymptomatic disease but it might be related with advanced end-organ damage. Parathyroid incidentaloma (PI) is the term describing enlarged parathyroid nodules that are unexpectedly discovered on surgery or by imaging performed for nonparathyroid disorders. The recognition of PI might uncover a clinically significant PHPT with the potential for surgical cure. We retrospectively reviewed patients’ reco...

Parathyroid localization by fine needle aspiration and parathyroid hormone (PTH) washout measurement is not a widely accepted method because of possible alterations in parathyroid histology. However, when performed with technical competence this easily available method has been praised to be an immediate confirmation of enlarged parathyroid glands found on ultrasound. We retrospectively reviewed primary hyperparathyroidism (PHPT) patients with previously performed PTH washout ...

Although primary hyperparathyroidism (PHPT) can be successfully cured by parathyroidectomy (PTX) and indications for surgery are well defined, a considerable number of patients do not get operated on. By evaluating referrals for PTX in our academic hospital, we might improve our approach to the care of these patients. We retrospectively reviewed patients’ hospital records with newly diagnosed PHPT between 2014 and 2020. Biochemical and clinical parameters along with resul...